The exon 3 is flanked with loxP sites and a neomycin selection segment flanked with FRT sites were inserted into the Krt8 gene. The neomycin segment was then removed using flp recombinase, leaving the loxP sites intact flanking exon 3. (J:332898)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count