The targeting construct inserted upstream of exon 2 a FRT-flanked beta-geo cassette and loxP site. A second loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the reporter/selection cassette. (J:214778)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count