An FRT-flanked IRES-lacZ/neomycin resistance gene cassette and loxP site were inserted upstream of exon 8 and a second loxP site was inserted downstream of the 3 UTR. The lacZ/neomycin selection cassette was removed via flp-mediated recombination leaving exons 8-11 and the 3 UTR floxed. (J:262771)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count