The endogenous mouse imprinting control region IC1 and 1.3-kb G-rich repeat sequence were replaced with human IC1. The inserted loxP-flanked neomycin resistance cassette was removed via cre-mediated recombination. (J:238342)
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The endogenous mouse imprinting control region IC1 and 1.3-kb G-rich repeat sequence were replaced with human IC1. The inserted loxP-flanked neomycin resistance cassette was removed via cre-mediated recombination. (J:238342)