The following were inserted into intron 5 (after the second coding exon): an FRT site, En2 splice acceptor sequence, an IRES, the lacZ beta-galactosidase gene, poly(A) signal sequence, a loxP site, a neomycin resistance gene cassette, a second FRT site and a second loxP site. A third loxP site was inserted downstream of the gene after exon 6. This creates a knockout allele. (J:331393)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Applicable
Targeted
Insertion, Intragenic deletion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Comparison
Al agent
Tutorials
Back to top