An FRT-flanked PGK-neomycin selection cassette and loxP site were inserted upstream of exon 3 and a second loxP site was inserted downstream of exon 3. The neomycin selection cassette was removed via flp-mediated recombination leaving exon 3 floxed. (J:256512)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count