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The targeted vector with an auto-excision floxed Neomycin resistance cassette and a 1.5 kb fragment corresponding to the fusion of the Venus tag sequence at the beginning of exon1 of the Shank3 gene, just after the ATG start codon was inserted. The floxed selection cassette was excised in the germline chimera mice. The reporter is to tag exclusively the endogenous Shank3 variants that are produced by the first promoter: variants of the Shank3a isoform only. (J:332650)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
