A CAG-loxP-Stop-loxP-V5-Map2k5 cDNA containing a serine to aspartate substitution at amino acid 311 (p.S311D) and a threonine to aspartate substitution at amino acid 315 (p.T315D)-polyA cassette was inserted into intron 1 via CRISPR/Cas9 technology. (J:328655)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count