This allele was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of CAGGGAGACACCGCTCATAA targeting the 5' side and TGGAGAAGTTGATTCTTACC targeting the 3' side of a critical region (ENSMUSE00000373130, ENSMUSE00000173330 & ENSMUSE00000173319). This resulted in a 3,276-bp deletion of Chr3 from 63,894,860 to 63,898,135 (GRCm39). (J:265051)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count