The targeting construct inserted a loxP site, splice acceptor, STOP cassette, FRT-flanked neomycin resistance cassette, and loxP site after exon 1 and a triple HA tag at the C-terminus of the coding sequence. Flp-mediated recombination removed the selection cassette. (J:329946)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count