A loxP site and an FRT-flanked selection cassette was inserted upstream of exon 2 and a second loxP site downstream of exon 2. The selection cassette was removed via flp-mediated recombination leaving exon 2 floxed. (J:322019)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count