Log In|Sign Up
EN
A 6.7 kb transgenic vector was generated including the mouse dopachrome tautomerase (Dct) promoter driving expression of a cre/ERT2 fusion gene (a Cre recombinase fused to a human estrogen receptor ligand binding domain) followed by an SV40 polyadenylation sequence. The founder line 40A, with approximately 60 copies of the transgene inserted into the H4 region (AC121292.9) of chromosome 1 in an intergenic region between the H3.3 histone A (H3f3a) and the SDE2 telomere maintenance homolog (S. pombe) (Sde2) genes, was established. (J:314330)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
