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This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CATATGTGCAAAAGATACCA and TGGAGGATAGATATACCACA, which resulted in a 383 bp deletion beginning at Chromosome 11 position 120,716,830 bp and ending after 120,717,212 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000148250 (exon 7) and 270 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 220 and early truncation 18 amino acids later. (J:188991)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
