A loxP flanked neomycin gene was inserted upstream of exon 5 and a third loxP site was inserted downstream of exon 8. The neomycin gene was removed via cre-mediated recombination leaving exons 5-8 floxed. (J:177486, J:273975)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count