An Ametrine-2A and FlpO (a codon-optimized flippase) cDNS followed by a 2A peptide linker was inserted after the ATG start codon of the Foxp3 gene with a AttB-Neo-AttP cassette. Germline mice were then crossed with Rosa.PhiC31 mice to remove the Neo cassette. (J:312516)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6N-Atm1Brd
Targeted
Insertion
--
1
4
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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