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A 562base pair fragment of the Zbtb7b silencer sequence was inserted into a mini-transgene containing the minimal Cd4 enhancer-promoter-FRT-icre/ERT2. A FRT site was inserted 1086bp upstream of the ATG codon of the icre/ERT2. The sequence encoding an internal ribosomal entry site and human CD2 were also inserted downstream of the cDNA cassette encoding icre/ERT2 and additional FRT site was inseted after the STOP codon of the CD2. The transgene expresses Cre specifically in the CD4 lineage. Founder information was not available. Line number 13 was assigned for the transgene inserted into chromosome 13 at approximately 13D1. (J:312516)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
