A construct containing a floxed-stop cassette followed by a CAG promoter driving expression of a GFP gene and sequence for a GA-175 dipeptide repeat protein encoded using non-repeating alternate codons was inserted into the cassette exchange locus in the Gt(ROSA)26Sortm1Rkuhn allele by recombinase mediate recombination. (J:324626)
Basic Information
(C57BL/6J x 129S6/SvEvTac)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count