A construct containing a floxed-stop cassette followed by a CAG promoter driving expression of a GFP gene and sequence for a GA-175 dipeptide repeat protein encoded using non-repeating alternate codons was inserted into the cassette exchange locus in the Gt(ROSA)26Sortm1Rkuhn allele by recombinase mediate recombination. (J:324626)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6J x 129S6/SvEvTac)F1
Targeted
Insertion
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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