For the transgene insert, genomic sequence from approximately -308 bp (relative to Gata3 transcription start site in CD-1 strain) to the 5' end of intron 2 (which includes upstream regulatory sequences, exon 1b, intron 1b, exon 2 and part of intron 2) was modified by the insertion of a beta-galactosidase reporter gene cassette (which includes poly(A) signal sequence) in place of the Gata3 ATG start site. The reporter is expressed in embryo limb bud muscle and intercostal muscle. (J:332297)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
CD-1
--
Insertion
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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