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A loxP-flanked STOP cassette (containing neomycin gene), GFP, and myc tag fused to the N-terminus of Ago2 coding sequence under the control of the CAG promoter were inserted into the locus. Only upon cre-mediated recombination to remove the STOP cassette is GFP and myc-tagged Ago2 expressed. GFP expression indicates expression of Ago2 and the myc epitotpe tag allows for affinity purification of associated miRNAs. (J:179351)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
