A loxP site was inserted upstream of exon 2 and an FRT-flanked neomycin resistance gene and second loxP site were inserted downstream of exon 5. The neomycin resistance gene was removed via flp-mediated recombination leaving exons 2-5 floxed. (J:202481)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count