The transgene contains a ~120 kb B1 repeat deletion subfragment of ~485 kb C3H YAC ICRFy903F1113. The YAC contains the entire Gata3 gene plus upstream and downstream regulatory regions and was modified by inserting a lacZ beta-galactosidase reporter gene cassette immediately downstream of (in-frame with) the Gata3 ATG start site. The reporter gene is expressed in many but not all tissues that normally express Gata3 during embryonic development. Seventeen mouse lines were established. (J:51930)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Applicable
--
Insertion
--
--
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Comparison
Al agent
Tutorials
Back to top