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The transgene contains a ~625 kb B1 repeat deletion subfragment of ~825 kb C57BL/6 YAC ICRFy902H125. The YAC contains the entire Gata3 gene plus upstream and downstream regulatory regions and was modified by inserting a lacZ beta-galactosidase reporter gene cassette immediately downstream of (in-frame with) the Gata3 ATG start site. The reporter gene is expressed in many but not all tissues that normally express Gata3 during embryonic development. (J:52950)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
