Log In|Sign Up
EN
The transgene insert contains the following elements: an FRT site flanked neomycin resistance gene cassette, Gata3 promoter 1b (-1314 to +1 relative to ATG start site; contains downstream promoter, alternative 1st exon 1b, intron 1b and 5' UTR part of exon 2), the EGFP reporter gene cDNA, and BAC RP23-43G17 (which contains Gata3 T cell and thymic NK cell enhancer (7.1 kb KpnI-SalI T cell element) Rr338) where Rr338 was replaced with an FRT site flanked neomycin resistance gene cassette. The neo cassettes were removed through subsequent flp-mediated recombination. EGFP expression is not observed in thymocytes anymore. (J:281897)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
