Coding exon 7 (genomic exon 8) was flanked by loxP sites. An FRT-flanked neomycin phosphotransferase cassette was inserted in between exon 7 and the second loxP site and removed via flp-mediated recombination. (J:264787)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count