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Cre-mediated inter-chromosomal recombination between Tn(sb-SBlac)15.195052Fsp at chr15:63208247-63208248 (GRCm39) and Tn(sb-SBlac)15.193315Fsp at chr15:63501716-63501717 deleted approximately 293 kb and leaves one intact copy of the transposon cassette (in reverse orientation) at the deletion junction. The transposon consists of a Sleeping Beauty transposon inverted repeat, loxP site, human beta-globin HBB minimal promoter, the lacZ beta-galactosidase reporter gene, SV40 poly(A) signal sequence, and a Sleeping Beauty transposon direct repeat. The deleted sequence is part of the Myc topologically associating domain (TAD) and contains Myc enhancers Rr334, Rr316124 and Rr313933. (J:212391)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
