Cre-mediated inter-chromosomal recombination between Tn(sb-SBlac)15.188150Fsp at chr15:62602119-62602120 (GRCm39) and Tn(sb-SBlac)15.193970Fsp at chr15:62894062-62894063 deleted approximately 292 kb and leaves one intact copy of the transposon cassette (in reverse orientation) at the deletion junction. The transposon consists of a Sleeping Beauty transposon inverted repeat, loxP site, human beta-globin HBB minimal promoter, the lacZ beta-galactosidase reporter gene, SV40 poly(A) signal sequence, and a Sleeping Beauty transposon direct repeat. The deleted sequence is part of the Myc topologically associating domain (TAD). (J:212391)
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基础信息

模型ID
品系来源
等位基因类型
突变
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Not Applicable
Transposon induced
Intergenic deletion
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标签摘要:
hm: 纯合子
ht: 杂合子
cn: 条件基因型
cx: 复合型:涉及多基因组
tg: 转基因
ot: 其他:半合子、不确定...
(F): 雌性
(M): 雄性
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(#): 上标括号内为相关疾病数量
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