Cre-mediated inter-chromosomal recombination between Tn(sb-SBlac)15.193637Fsp at chr15:63236763-63236764 (GRCm39) and Tn(sb-SBlac)15.179039Fsp at chr15:63590844-63590845 deleted approximately 354 kb and leaves one intact copy of the transposon cassette (in forward orientation) at the deletion junction. The transposon consists of a Sleeping Beauty transposon inverted repeat, loxP site, human beta-globin HBB minimal promoter, the lacZ beta-galactosidase reporter gene, SV40 poly(A) signal sequence, and a Sleeping Beauty transposon direct repeat. The deleted sequence is part of the Myc topologically associating domain (TAD) and contains Myc enhancers Rr334, Rr316124, Rr313933, Rr331, Rr307328, Rr332, Rr307330, Rr333 and Rr313939. (J:212391)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
Transposon induced
Insertion, Intergenic deletion
--
--
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Comparison
Al agent
Tutorials
Back to top