CRISPR-targeting using an sgRNA (targeting TGGAAGGCCACTTCCCAGAA) deleted 11 bp (CTTCCCAGAAG), which includes the interferonactivated sequence (GAS) motif, within the E1 enhancer (part of Wap super enhancer) upstream of Wap. (J:277922)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
Endonuclease-mediated
Intergenic deletion
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--
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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