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Border (insulator) region Rr325 in In(11Rr325)1Smun inversion allele ES cells (originally located between the Kcnj and Sox9 topologically associated domains (TADs)), was targeted with sgRNAs (targeting ATCCCGAAATTAAACTGCCC and CTTCTTAACAAAAACCGAAC) using CRISPR/Cas9 technology, resulting in its deletion. (J:282642)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
