Exon 11 was flanked with loxP sites. The inserted FRT-flanked neomycin stop cassette was removed via flp-mediated recombination. Exon 11 was deleted via cre-mediated recombination in the germline. (J:331735)
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Exon 11 was flanked with loxP sites. The inserted FRT-flanked neomycin stop cassette was removed via flp-mediated recombination. Exon 11 was deleted via cre-mediated recombination in the germline. (J:331735)