A loxP site and FRT-flanked neomycin resistance gene were inserted upstream of exon 4 and a second loxP site was inserted downstream of exon 18. The neomycin resistance gene was removed via flp-mediated recombination leaving exons 4-18 floxed. (J:331744)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count