A loxP site was introduced into intron 6 and a floxed Hyg-TK selection cassette into intron 7. The selection cassette were removed by transient Cre expression, leaving a floxed exon 7. (J:308372)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count