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This duplication allele was created through cre-mediated interchromosomal recombination between loxP sites on two alleles: allele Igs46em1Smun containing a single loxP site at chr11:110801622-110801623 (GRCm39), the other a derivative of allele IIgs44tm1(sb-SBlac)Smun where the SBlac transposon cassette was remobilized using the Tg(Prm1-sb16)AFsp allele and re-inserted at (hopped to) chr11:111403236-111403237. It duplicates around half of the Kcnj topologically associated domain (TAD) and the Kcnj16 and Kcnj2 genes it contains. (J:235642)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
