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A human transforming RET cDNA was isolated from a cDNA library of a THP-1 human monocytic leukemia cell line in which the sequences encoding the last 51 carboxy-terminal amino acids of the ret proto-oncogene were replaced with sequences encoding 9 unrelated amino acids. This cDNA was expressed under the control of the Emu enhancer (Rr150) from the immunoglobulin heavy chain (Igh) gene. (J:276582)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
