A bacterial artificial chromosome (BAC; RP23-151J22) containing the mouse smooth muscle myosin, heavy polypeptide 11 (Myh11) gene was used to insert a cre/ERT2 sequence (a mutated human estrogen receptor ligand binding domain fused to Cre) at the start codon of Myh11. The founder line F31, in which the transgene integrated into mouse Chromosome 2 in a region devoid of other genes [Chr2:178,826,578-178,826,802 (GRCm39)], was identified. (J:332260)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6N
--
Insertion
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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