CRISPR/Cas9 technology inserted loxP sites flanking exon 7, which encodes the RING1 domain and is essential for PARKIN E3 ligase activity. (J:331734)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count