The transgene insert contains a 22.5-kb human TCRD gene minilocus consisting of germline Vdelta1, Vdelta2, Ddelta3, Jdelta1, Jdelta3, and Cdelta gene segments and all "intronic" sequence between, including enhancer sequence between Jdelta3 and Cdelta where Ets-binding site TCCTC was mutated to AGTTC. (J:330514)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x SJL/J)F2
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Insertion
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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