Ndrg3^{tm1c(KOMP)Wtsi}

The L1L2_gt0 cassette was inserted at position 156791669 of Chromosome 2 upstream of the critical exon 4 (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon 4 at position 156792496. The critical exon 4 is thus flanked by loxP sites. The lacZ/neomycin were removed via flp-mediated recombination generating a conditional ready exon 4 floxed allele. (J:330551)