The transgene contains the following elements: SV40 transcriptional terminator sequence, mouse Il4 promoter/enhancer sequence (-741 to + 60 bp with respect to TATA box start), the luciferase gene, and SV40 poly(A) signal sequence. A total of four mouse lines were created (#32, 66, 72, 85), with transgene copy numbers of 4-50. (J:40450)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count