The transgene insert consists of BAC clone RP24-348O11 where the Thy1 cDNA coding region and SV40 poly(A) signal sequence were inserted into Ifng exon 1 immediately downstream of the ATG start site (replacing the remainder of the exon 1 coding region), upstream Ifng cis-control region CNS-22 (Rr32) was flanked by loxP sites, and an FRT site flanked kanamycin resistance gene cassette was inserted between Rr32 and Ifng. The kana cassette was removed through subsequent flp-mediated recombination. (J:116207)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Applicable
--
Insertion
--
--
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Comparison
Al agent
Tutorials
Back to top