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The transgenic construct contains the human KRT14 promoter/enhnacer directing expression of a beta globin intron and a loxP-flanked EGFP/STOP, and the E6 and E7 early genes from Human papilloma virus followed by a KRT14 polyA signal. It is estimated that there are about 18 copies of the transgene per homozyous cell. This allele is founder #14. (J:299115)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
