The targeting construct inserted into a neutral location in chromosome 1 an antioxidant responsive element (minimal Nfe2l2 promoter; four selected Nfe2l2 responsive elements repeated twice), luciferase reporter gene, and tdTomato reporter gene. Cre-mediated recombination removed the floxed stop cassette. (J:250245)
Basic Information
(C57BL/6J x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count