The targeting construct inserted into a neutral location in chromosome 1 an antioxidant responsive element (minimal Nfe2l2 promoter; four selected Nfe2l2 responsive elements repeated twice), luciferase reporter gene, and tdTomato reporter gene. Cre-mediated recombination removed the floxed stop cassette. (J:250245)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6J x 129S4/SvJae)F1
Targeted
Insertion
--
--
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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