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EN
TALEN-targeting using a homologous donor molecule created a G-to-A point mutation at chr7:142217981 (GRCm39) in the a multi-species conserved consensus sequence bound by a repressor, ZBED6, and created a silent A-to-G mutation at chr7:142217996 to disrupt one of the TALEN binding sites to prevent re-cleavage. (J:331260)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
