A 1 kb PvuII-BamHI genomic fragment containing Tcra enhancer Ealpha was replaced with a sequence containing a loxP site flanked neomycin resistance gene cassette and a 700 bp XbaI-EcoRI fragment containing Igh enhancer iEmu (Rr150). The neo cassette was subsequently deleted through cre-mediated recombination. (J:82395)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S6/SvEvTac
Targeted
Insertion, Intergenic deletion
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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