CRISPR/Cas9 technology targeted the SET domain of Setd1a inserting a two-nucleotide at the start of the SET domain in exon 17, resulting in an early stop codon that removes the majority of the SET domain (J:331091)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count