The targeting construct introduced the tdiRFP713NLS reporter gene expressed under CAG promoter and WPRE sequence into 3 UTR region. Both cre- and flp-mediated recombination is required to achieve expression of the reporter. FRT-Stop-FRT cassette was removed by crossing pCAG-FLPe strain. The HA-epitope tga was is attched to tdiFP713NLS. (J:104881)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count