CRISPR/cas9 genome editing technology is used to insert a cre-inducible affinity tag, StrepTagII, into intron 1 of the gene. The vector included two pairs of inward-facing heterospecific Lox sites (loxP and lox2272) flanking an inverted StrepTagII. (J:330295)
Basic Information
(B6.129P2-Trp53tm1Brn/J x B6(129X1)-Dstem13Dcr/DcrJ)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count