CRISPR/cas9 genome editing technology is used to insert a cre-inducible affinity tag, StrepTagII, into intron 1 of the gene. The vector included two pairs of inward-facing heterospecific Lox sites (loxP and lox2272) flanking an inverted StrepTagII. (J:330295)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(B6.129P2-Trp53tm1Brn/J x B6(129X1)-Dstem13Dcr/DcrJ)F1
Endonuclease-mediated
Insertion
--
1
12
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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