The adjacent cardiac Cacna1g and Epn3 enhancers, located in an intron of Cacna1g, were targeted with sgRNAs (targeting GGGCACATCCCTCAGCAGCC and GGCCCAATTAGAAGCCACCC) using CRISPR/Cas9 technology, resulting in a 3345 bp deletion. (J:295904)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/NRj
Endonuclease-mediated
Intragenic deletion
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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