This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CTGGATGGCTCCCTAAGACA and TAGAATAGACTCAAACTCCA, which resulted in a 593 bp deletion beginning at Chromosome 14 position 62,674,033 bp and ending after 62,674,625 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000883429 (exon 5) and 394 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 231 and early truncation 8 amino acids later. (J:188991)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count