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This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences AGGACATCCCAGCAGTGCTC and ATAACAGATGAATTGTAGAA, which resulted in a 3534 bp deletion beginning at Chromosome 11 position 68,892,320 bp and ending after 68,895,853 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000466988 (exon 3) and 339 bp of flanking intronic sequence including the start site, splice acceptor and donor and is predicted to result in a null allele. (J:188991)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
